Nictiz FHIR NL STU3 Zib2017
1.3.15 - CI Build

Nictiz FHIR NL STU3 Zib2017 - Local Development build (v1.3.15) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

Resource Profile: Zib Dispense - Detailed Descriptions

Active as of 2025-09-22

Definitions for the zib-Dispense resource profile.

Guidance on how to interpret the contents of this table can be foundhere

0. MedicationDispense
ShortMedicationDispense
Alternate NamesVerstrekking
2. MedicationDispense.extension
SlicingThis element introduces a set of slices on MedicationDispense.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
  • value @ url
  • 4. MedicationDispense.extension:distributionForm
    Slice NamedistributionForm
    Definition

    Distribution form.

    ShortDistributionForm
    Comments

    For example through Baxter or seperate box.

    Control0..1
    TypeExtension(HCIM Dispense Distribution Form) (Extension Type: CodeableConcept)
    Alternate NamesDistributievorm
    6. MedicationDispense.extension:distributionForm.valueCodeableConcept:valueCodeableConcept
    Slice NamevalueCodeableConcept
    BindingUnless not suitable, these codes SHALL be taken from MedicatieverstrekkingDistributievormCodelijst
    (extensible to http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.9.1--20171231000000)

    VerstrekkingDistributievormCodelijst

    8. MedicationDispense.extension:requestDate
    Slice NamerequestDate
    Definition

    The time at which a pharmacist records an intended dispense.

    ShortRequestDate
    Control0..1
    TypeExtension(HCIM Dispense RequestDate) (Extension Type: dateTime)
    Alternate NamesAanschrijfdatum
    10. MedicationDispense.extension:additionalInformation
    Slice NameadditionalInformation
    Definition

    Additional information includes details on the structure of the dispense. This can be e.g. a reason for deviating from the dispense request. For now, this list is used. This list will be replaced by a thesaurus in the G standard at a later stage.

    ShortDispenseAdditionalInformation
    Control0..1
    TypeExtension(HCIM AdditionalInformation) (Extension Type: CodeableConcept)
    Alternate NamesVerstrekkingAanvullendeInformatie
    12. MedicationDispense.extension:additionalInformation.valueCodeableConcept:valueCodeableConcept
    Slice NamevalueCodeableConcept
    BindingUnless not suitable, these codes SHALL be taken from MedicatieverstrekkingAanvullendeInformatieCodelijst
    (extensible to http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.9.2--20171231000000)

    VerstrekkingAanvullendeInformatieCodelijst

    ExampleExample of DispenseAdditionalInformation: { "coding" : [{ "system" : "urn:oid:2.16.840.1.113883.2.4.3.11.60.20.77.5.2.3.2052", "code" : "1", "display" : "Aantal bewust gewijzigd" }] }
    14. MedicationDispense.extension:medicationTreatment
    Slice NamemedicationTreatment
    Definition

    This extension is to describe which overarching medication treatment this information is part of. This is done by the use of an identifier of that medication treatment.

    ShortMedication Treatment
    Comments

    No HCIM concept is available for this element. Therefore a mapping to the relevant element Medication Process data element is provided.

    Control0..1
    TypeExtension(HCIM MedicationTreatment) (Extension Type: Identifier)
    Alternate NamesMedicamenteuze behandeling
    16. MedicationDispense.identifier
    NoteThis is a business identifier, not a resource identifier (see discussion)
    18. MedicationDispense.partOf
    TypeReference(HCIM Procedure)
    20. MedicationDispense.category
    Control1..?
    22. MedicationDispense.category.coding
    SlicingThis element introduces a set of slices on MedicationDispense.category.coding. The slices areUnordered and Open, and can be differentiated using the following discriminators:
    • value @ code
    • 24. MedicationDispense.category.coding:DispenseCode
      Slice NameDispenseCode
      Definition

      Category SNOMED code used for indexing/retrieval of the HCIM Dispense. The SNOMED code 373784005 for this resource is stated in the Medication Process v09.

      ShortDispenseCode
      26. MedicationDispense.category.coding:DispenseCode.system
      Fixed Valuehttp://snomed.info/sct
      28. MedicationDispense.category.coding:DispenseCode.code
      Fixed Value373784005
      30. MedicationDispense.category.coding:DispenseCode.display
      Default ValueDispensing medication (procedure)
      32. MedicationDispense.medicationReference:medicationReference
      Slice NamemedicationReference
      Definition

      The dispensed medicine.

      ShortDispensedMedicine
      TypeReference(HCIM PharmaceuticalProduct)
      Alternate NamesVerstrekGeneesmiddel
      34. MedicationDispense.subject
      TypeReference(nl-core-patient, Group)
      36. MedicationDispense.context
      TypeReference(HCIM Encounter, nl-core-episodeofcare)
      38. MedicationDispense.performer
      Definition

      In almost all cases, the supplier will be a pharmacist. It could also be supplied by a webshop (in case of an online order), a drug store or a foreign pharmacist.

      ShortSupplier
      Alternate NamesVerstrekker
      40. MedicationDispense.performer.actor
      Comments

      The health professional's speciality, role, and organization are captured and communicated through the PractitionerRole Resource based on the nl-core-practitionerrole profile.

      TypeReference(nl-core-practitioner, nl-core-organization, nl-core-patient, HCIM MedicalDevice Product, nl-core-relatedperson)
      42. MedicationDispense.performer.actor.extension
      SlicingThis element introduces a set of slices on MedicationDispense.performer.actor.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
      • value @ url
      • 44. MedicationDispense.performer.actor.extension:practitionerRole
        Slice NamepractitionerRole
        Control0..1
        TypeExtension(PractitionerRole Reference) (Extension Type: Reference)
        46. MedicationDispense.performer.onBehalfOf
        TypeReference(nl-core-organization)
        48. MedicationDispense.authorizingPrescription
        Definition

        Relationship to the dispense request.

        ShortDispenseRequest
        Control0..1
        TypeReference(HCIM DispenseRequest)
        Alternate NamesVerstrekkingsverzoek
        50. MedicationDispense.quantity
        Definition

        Number of units of the product (measured based on the relevant product code) supplied.

        ShortDispensedAmount
        Alternate NamesVerstrekteHoeveelheid
        52. MedicationDispense.daysSupply
        Definition

        The period in which the medication is expected to be used. The value depends on the dose and the dispensed amount.

        ShortDurationOfUse
        Alternate NamesVerbruiksDuur
        54. MedicationDispense.whenHandedOver
        Definition

        The time at which the medicine was supplied. The date and time at which the medicine is delivered.
        Note: this is the time at which the medicine was delivered to the patient (or their administrator/representative) and not the request date.

        ShortDispenseDateTime
        Alternate NamesVerstrekkingsDatumTijd
        ExampleExample of DispenseDateTime: 2017-05-17
        56. MedicationDispense.destination
        Definition

        Dispense location.

        ShortDispenseLocation
        TypeReference(nl-core-location)
        Alternate NamesAfleverlocatie
        58. MedicationDispense.receiver
        TypeReference(nl-core-patient, nl-core-practitioner)
        60. MedicationDispense.receiver.extension
        SlicingThis element introduces a set of slices on MedicationDispense.receiver.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
        • value @ url
        • 62. MedicationDispense.receiver.extension:practitionerRole
          Slice NamepractitionerRole
          Control0..1
          TypeExtension(PractitionerRole Reference) (Extension Type: Reference)
          64. MedicationDispense.note
          Definition

          Comments or additional information on the dispense. Additional information includes details on the structure of the dispense. This can be e.g. a reason for deviating from the dispense request.

          ShortComment
          Alternate NamesToelichting, Aanvullende informatie
          66. MedicationDispense.dosageInstruction
          Definition

          Dosage instructions are part of an AdministrationAgreement

          Control0..0

          Guidance on how to interpret the contents of this table can be foundhere

          0. MedicationDispense
          Definition

          Indicates that a medication product is to be or has been dispensed for a named person/patient. This includes a description of the medication product (supply) provided and the instructions for administering the medication. The medication dispense is the result of a pharmacy system responding to a medication order.

          ShortMedicationDispenseDispensing a medication to a named patient
          Comments

          The WG will be updating the MedicationDispense resource to adjust each affected resource to align with the workflow pattern (see workflow.html).

          Control0..*
          Alternate NamesVerstrekking
          Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
          dom-1: If the resource is contained in another resource, it SHALL NOT contain any narrative (contained.text.empty())
          dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
          dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource (contained.where(('#'+id in %resource.descendants().reference).not()).empty())
          mdd-1: whenHandedOver cannot be before whenPrepared (whenHandedOver.empty() or whenPrepared.empty() or whenHandedOver >= whenPrepared)
          dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
          dom-1: If the resource is contained in another resource, it SHALL NOT contain any narrative (contained.text.empty())
          dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
          dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource (contained.where(('#'+id in %resource.descendants().reference).not()).empty())
          mdd-1: whenHandedOver cannot be before whenPrepared (whenHandedOver.empty() or whenPrepared.empty() or whenHandedOver >= whenPrepared)
          2. MedicationDispense.implicitRules
          Definition

          A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content.

          ShortA set of rules under which this content was created
          Comments

          Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element.

          This element is labelled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation.

          Control0..1
          Typeuri
          Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
          Summarytrue
          4. MedicationDispense.extension
          Definition

          An Extension


          May be used to represent additional information that is not part of the basic definition of the resource. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

          ShortExtensionAdditional Content defined by implementations
          Comments

          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

          Control0..*
          TypeExtension
          Alternate Namesextensions, user content
          SlicingThis element introduces a set of slices on MedicationDispense.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
          • value @ url
          • 6. MedicationDispense.extension:distributionForm
            Slice NamedistributionForm
            Definition

            Distribution form.

            ShortDistributionForm
            Comments

            For example through Baxter or seperate box.

            Control0..1
            This element is affected by the following invariants: ele-1
            TypeExtension(HCIM Dispense Distribution Form) (Extension Type: CodeableConcept)
            Alternate NamesDistributievorm
            Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
            ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
            8. MedicationDispense.extension:distributionForm.url
            Definition

            Source of the definition for the extension code - a logical name or a URL.

            Shortidentifies the meaning of the extension
            Comments

            The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

            Control1..1
            Typeuri
            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
            XML FormatIn the XML format, this property is represented as an attribute.
            Fixed Valuehttp://nictiz.nl/fhir/StructureDefinition/zib-Dispense-DistributionForm
            10. MedicationDispense.extension:distributionForm.value[x]
            Definition

            Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

            ShortValue of extension
            Control0..1
            TypeCodeableConcept, date, dateTime, Meta, code, string, Address, Attachment, integer, oid, Count, instant, ContactPoint, HumanName, Money, Identifier, Coding, markdown, SampledData, Ratio, id, positiveInt, Age, Distance, Reference, Period, Quantity, Duration, Range, uri, Annotation, boolean, base64Binary, Signature, unsignedInt, time, Timing, decimal
            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
            SlicingThis element introduces a set of slices on MedicationDispense.extension.value[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
            • type @ $this
            • 12. MedicationDispense.extension:distributionForm.value[x]:valueCodeableConcept
              Slice NamevalueCodeableConcept
              Definition

              Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

              ShortValue of extension
              Control0..1
              BindingUnless not suitable, these codes SHALL be taken from For codes, see MedicatieverstrekkingDistributievormCodelijst
              (extensible to http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.9.1--20171231000000)

              VerstrekkingDistributievormCodelijst

              TypeCodeableConcept, date, dateTime, Meta, code, string, Address, Attachment, integer, oid, Count, instant, ContactPoint, HumanName, Money, Identifier, Coding, markdown, SampledData, Ratio, id, positiveInt, Age, Distance, Reference, Period, Quantity, Duration, Range, uri, Annotation, boolean, base64Binary, Signature, unsignedInt, time, Timing, decimal
              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
              14. MedicationDispense.extension:requestDate
              Slice NamerequestDate
              Definition

              The time at which a pharmacist records an intended dispense.

              ShortRequestDate
              Control0..1
              This element is affected by the following invariants: ele-1
              TypeExtension(HCIM Dispense RequestDate) (Extension Type: dateTime)
              Alternate NamesAanschrijfdatum
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
              16. MedicationDispense.extension:additionalInformation
              Slice NameadditionalInformation
              Definition

              Additional information includes details on the structure of the dispense. This can be e.g. a reason for deviating from the dispense request. For now, this list is used. This list will be replaced by a thesaurus in the G standard at a later stage.

              ShortDispenseAdditionalInformation
              Control0..1
              This element is affected by the following invariants: ele-1
              TypeExtension(HCIM AdditionalInformation) (Extension Type: CodeableConcept)
              Alternate NamesVerstrekkingAanvullendeInformatie
              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
              18. MedicationDispense.extension:additionalInformation.url
              Definition

              Source of the definition for the extension code - a logical name or a URL.

              Shortidentifies the meaning of the extension
              Comments

              The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

              Control1..1
              Typeuri
              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
              XML FormatIn the XML format, this property is represented as an attribute.
              Fixed Valuehttp://nictiz.nl/fhir/StructureDefinition/zib-Medication-AdditionalInformation
              20. MedicationDispense.extension:additionalInformation.value[x]
              Definition

              Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

              ShortValue of extension
              Control0..1
              TypeCodeableConcept, date, dateTime, Meta, code, string, Address, Attachment, integer, oid, Count, instant, ContactPoint, HumanName, Money, Identifier, Coding, markdown, SampledData, Ratio, id, positiveInt, Age, Distance, Reference, Period, Quantity, Duration, Range, uri, Annotation, boolean, base64Binary, Signature, unsignedInt, time, Timing, decimal
              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
              SlicingThis element introduces a set of slices on MedicationDispense.extension.value[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
              • type @ $this
              • 22. MedicationDispense.extension:additionalInformation.value[x]:valueCodeableConcept
                Slice NamevalueCodeableConcept
                Definition

                Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

                ShortValue of extension
                Control0..1
                BindingUnless not suitable, these codes SHALL be taken from For codes, see MedicatieverstrekkingAanvullendeInformatieCodelijst
                (extensible to http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.9.2--20171231000000)

                VerstrekkingAanvullendeInformatieCodelijst

                TypeCodeableConcept, date, dateTime, Meta, code, string, Address, Attachment, integer, oid, Count, instant, ContactPoint, HumanName, Money, Identifier, Coding, markdown, SampledData, Ratio, id, positiveInt, Age, Distance, Reference, Period, Quantity, Duration, Range, uri, Annotation, boolean, base64Binary, Signature, unsignedInt, time, Timing, decimal
                [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                ExampleExample of DispenseAdditionalInformation: { "coding" : [{ "system" : "urn:oid:2.16.840.1.113883.2.4.3.11.60.20.77.5.2.3.2052", "code" : "1", "display" : "Aantal bewust gewijzigd" }] }
                24. MedicationDispense.extension:medicationTreatment
                Slice NamemedicationTreatment
                Definition

                This extension is to describe which overarching medication treatment this information is part of. This is done by the use of an identifier of that medication treatment.

                ShortMedication Treatment
                Comments

                No HCIM concept is available for this element. Therefore a mapping to the relevant element Medication Process data element is provided.

                Control0..1
                This element is affected by the following invariants: ele-1
                TypeExtension(HCIM MedicationTreatment) (Extension Type: Identifier)
                Alternate NamesMedicamenteuze behandeling
                Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                26. MedicationDispense.modifierExtension
                Definition

                May be used to represent additional information that is not part of the basic definition of the resource, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                ShortExtensions that cannot be ignored
                Comments

                There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                Control0..*
                TypeExtension
                Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                Alternate Namesextensions, user content
                28. MedicationDispense.identifier
                Definition

                Identifier assigned by the dispensing facility - this is an identifier assigned outside FHIR.

                ShortExternal identifier
                NoteThis is a business identifier, not a resource identifier (see discussion)
                Control0..*
                TypeIdentifier
                30. MedicationDispense.partOf
                Definition

                The procedure that the dispense is done because of.

                ShortEvent that dispense is part of
                Control0..*
                TypeReference(HCIM Procedure, Procedure)
                32. MedicationDispense.status
                Definition

                A code specifying the state of the set of dispense events.

                Shortpreparation | in-progress | on-hold | completed | entered-in-error | stopped
                Comments

                This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

                Control0..1
                BindingThe codes SHALL be taken from MedicationDispenseStatushttp://hl7.org/fhir/ValueSet/medication-dispense-status|3.0.2
                (required to http://hl7.org/fhir/ValueSet/medication-dispense-status|3.0.2)

                A coded concept specifying the state of the dispense event.

                Typecode
                Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                Summarytrue
                34. MedicationDispense.category
                Definition

                Indicates type of medication dispense and where the medication is expected to be consumed or administered.

                ShortType of medication dispense
                Control10..1
                BindingThe codes SHOULD be taken from MedicationDispenseCategoryhttp://hl7.org/fhir/ValueSet/medication-dispense-category|3.0.2
                (preferred to http://hl7.org/fhir/ValueSet/medication-dispense-category|3.0.2)

                A code describing where the dispensed medication is expected to be consumed or administered

                TypeCodeableConcept
                36. MedicationDispense.category.coding
                Definition

                A reference to a code defined by a terminology system.

                ShortCode defined by a terminology system
                Comments

                Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

                Control0..*
                TypeCoding
                Summarytrue
                Requirements

                Allows for translations and alternate encodings within a code system. Also supports communication of the same instance to systems requiring different encodings.

                SlicingThis element introduces a set of slices on MedicationDispense.category.coding. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                • value @ code
                • 38. MedicationDispense.category.coding:DispenseCode
                  Slice NameDispenseCode
                  Definition

                  Category SNOMED code used for indexing/retrieval of the HCIM Dispense. The SNOMED code 373784005 for this resource is stated in the Medication Process v09.


                  A reference to a code defined by a terminology system.

                  ShortDispenseCodeCode defined by a terminology system
                  Comments

                  Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

                  Control0..*
                  TypeCoding
                  Summarytrue
                  Requirements

                  Allows for translations and alternate encodings within a code system. Also supports communication of the same instance to systems requiring different encodings.

                  40. MedicationDispense.category.coding:DispenseCode.system
                  Definition

                  The identification of the code system that defines the meaning of the symbol in the code.

                  ShortIdentity of the terminology system
                  Comments

                  The URI may be an OID (urn:oid:...) or a UUID (urn:uuid:...). OIDs and UUIDs SHALL be references to the HL7 OID registry. Otherwise, the URI should come from HL7's list of FHIR defined special URIs or it should de-reference to some definition that establish the system clearly and unambiguously.

                  Control0..1
                  Typeuri
                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                  Summarytrue
                  Requirements

                  Need to be unambiguous about the source of the definition of the symbol.

                  Fixed Valuehttp://snomed.info/sct
                  42. MedicationDispense.category.coding:DispenseCode.code
                  Definition

                  A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).

                  ShortSymbol in syntax defined by the system
                  Control0..1
                  Typecode
                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                  Summarytrue
                  Requirements

                  Need to refer to a particular code in the system.

                  Fixed Value373784005
                  44. MedicationDispense.category.coding:DispenseCode.display
                  Definition

                  A representation of the meaning of the code in the system, following the rules of the system.

                  ShortRepresentation defined by the system
                  Control0..1
                  Typestring
                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                  Summarytrue
                  Requirements

                  Need to be able to carry a human-readable meaning of the code for readers that do not know the system.

                  46. MedicationDispense.medication[x]
                  Definition

                  Identifies the medication being administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications.

                  ShortWhat medication was supplied
                  Comments

                  If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended.  For example if you require form or lot number, then you must reference the Medication resource. .

                  Control1..1
                  TypeReference(Medication), CodeableConcept
                  [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                  Summarytrue
                  SlicingThis element introduces a set of slices on MedicationDispense.medication[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
                  • type @ $this
                  • 48. MedicationDispense.medication[x]:medicationReference
                    Slice NamemedicationReference
                    Definition

                    The dispensed medicine.


                    Identifies the medication being administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications.

                    ShortDispensedMedicineWhat medication was supplied
                    Comments

                    If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended.  For example if you require form or lot number, then you must reference the Medication resource. .

                    Control1..1
                    TypeReference(HCIM PharmaceuticalProduct, Medication), CodeableConcept
                    [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                    Summarytrue
                    Alternate NamesVerstrekGeneesmiddel
                    50. MedicationDispense.subject
                    Definition

                    A link to a resource representing the person or the group to whom the medication will be given.

                    ShortWho the dispense is for
                    Comments

                    SubstanceAdministration->subject->Patient.

                    Control0..1
                    TypeReference(nl-core-patient, Group, Patient)
                    Summarytrue
                    52. MedicationDispense.context
                    Definition

                    The encounter or episode of care that establishes the context for this event.

                    ShortEncounter / Episode associated with event
                    Control0..1
                    TypeReference(HCIM Encounter, nl-core-episodeofcare, Encounter, EpisodeOfCare)
                    54. MedicationDispense.performer
                    Definition

                    In almost all cases, the supplier will be a pharmacist. It could also be supplied by a webshop (in case of an online order), a drug store or a foreign pharmacist.


                    Indicates who or what performed the event. It should be assumed that the performer is the dispenser of the medication.

                    ShortSupplierWho performed event
                    Comments

                    The performer will be reviewed as part of STU4.

                    Control0..*
                    TypeBackboneElement
                    Alternate NamesVerstrekker
                    Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                    ele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                    56. MedicationDispense.performer.modifierExtension
                    Definition

                    May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                    ShortExtensions that cannot be ignored
                    Comments

                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                    Control0..*
                    TypeExtension
                    Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                    Summarytrue
                    Alternate Namesextensions, user content, modifiers
                    58. MedicationDispense.performer.actor
                    Definition

                    The device, practitioner, etc. who performed the action. It should be assumed that the actor is the dispenser of the medication.

                    ShortIndividual who was performing
                    Comments

                    The health professional's speciality, role, and organization are captured and communicated through the PractitionerRole Resource based on the nl-core-practitionerrole profile.

                    Control1..1
                    TypeReference(nl-core-practitioner, nl-core-organization, nl-core-patient, HCIM MedicalDevice Product, nl-core-relatedperson, Practitioner, Organization, Patient, Device, RelatedPerson)
                    60. MedicationDispense.performer.actor.extension
                    Definition

                    An Extension


                    May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                    ShortExtensionAdditional Content defined by implementations
                    Comments

                    There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                    Control0..*
                    TypeExtension
                    Alternate Namesextensions, user content
                    SlicingThis element introduces a set of slices on MedicationDispense.performer.actor.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                    • value @ url
                    • 62. MedicationDispense.performer.actor.extension:practitionerRole
                      Slice NamepractitionerRole
                      Definition

                      Optional Extension Element - found in all resources.

                      ShortOptional Extensions Element
                      Control0..1
                      TypeExtension(PractitionerRole Reference) (Extension Type: Reference)
                      64. MedicationDispense.performer.onBehalfOf
                      Definition

                      The organization the device or practitioner was acting on behalf of.

                      ShortOrganization organization was acting for
                      Control0..1
                      TypeReference(nl-core-organization, Organization)
                      66. MedicationDispense.authorizingPrescription
                      Definition

                      Relationship to the dispense request.


                      Indicates the medication order that is being dispensed against.

                      ShortDispenseRequestMedication order that authorizes the dispense
                      Comments

                      Maps to basedOn in Event logical model.

                      Control0..1*
                      TypeReference(HCIM DispenseRequest, MedicationRequest)
                      Alternate NamesVerstrekkingsverzoek
                      68. MedicationDispense.quantity
                      Definition

                      Number of units of the product (measured based on the relevant product code) supplied.


                      The amount of medication that has been dispensed. Includes unit of measure.

                      ShortDispensedAmountAmount dispensed
                      Control0..1
                      TypeQuantity(SimpleQuantity)
                      Alternate NamesVerstrekteHoeveelheid
                      70. MedicationDispense.daysSupply
                      Definition

                      The period in which the medication is expected to be used. The value depends on the dose and the dispensed amount.


                      The amount of medication expressed as a timing amount.

                      ShortDurationOfUseAmount of medication expressed as a timing amount
                      Control0..1
                      TypeQuantity(SimpleQuantity)
                      Alternate NamesVerbruiksDuur
                      72. MedicationDispense.whenHandedOver
                      Definition

                      The time at which the medicine was supplied. The date and time at which the medicine is delivered.
                      Note: this is the time at which the medicine was delivered to the patient (or their administrator/representative) and not the request date.


                      The time the dispensed product was provided to the patient or their representative.

                      ShortDispenseDateTimeWhen product was given out
                      Control0..1
                      TypedateTime
                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                      Alternate NamesVerstrekkingsDatumTijd
                      ExampleExample of DispenseDateTime: 2017-05-17
                      74. MedicationDispense.destination
                      Definition

                      Dispense location.


                      Identification of the facility/location where the medication was shipped to, as part of the dispense event.

                      ShortDispenseLocationWhere the medication was sent
                      Control0..1
                      TypeReference(nl-core-location, Location)
                      Alternate NamesAfleverlocatie
                      76. MedicationDispense.receiver
                      Definition

                      Identifies the person who picked up the medication. This will usually be a patient or their caregiver, but some cases exist where it can be a healthcare professional.

                      ShortWho collected the medication
                      Control0..*
                      TypeReference(nl-core-patient, nl-core-practitioner, Patient, Practitioner)
                      78. MedicationDispense.receiver.extension
                      Definition

                      An Extension


                      May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                      ShortExtensionAdditional Content defined by implementations
                      Comments

                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                      Control0..*
                      TypeExtension
                      Alternate Namesextensions, user content
                      SlicingThis element introduces a set of slices on MedicationDispense.receiver.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                      • value @ url
                      • 80. MedicationDispense.receiver.extension:practitionerRole
                        Slice NamepractitionerRole
                        Definition

                        Optional Extension Element - found in all resources.

                        ShortOptional Extensions Element
                        Control0..1
                        TypeExtension(PractitionerRole Reference) (Extension Type: Reference)
                        82. MedicationDispense.note
                        Definition

                        Comments or additional information on the dispense. Additional information includes details on the structure of the dispense. This can be e.g. a reason for deviating from the dispense request.


                        Extra information about the dispense that could not be conveyed in the other attributes.

                        ShortCommentInformation about the dispense
                        Control0..*
                        TypeAnnotation
                        Alternate NamesToelichting, Aanvullende informatie
                        84. MedicationDispense.dosageInstruction
                        Definition

                        Dosage instructions are part of an AdministrationAgreement


                        Indicates how the medication is to be used by the patient.

                        ShortHow the medication is to be used by the patient or administered by the caregiver
                        Comments

                        When the dose or rate is intended to change over the entire administration period (e.g. Tapering dose prescriptions), multiple instances of dosage instructions will need to be supplied to convey the different doses/rates. The pharmacist reviews the medication order prior to dispense and updates the dosageInstruction based on the actual product being dispensed.

                        Control0..0*
                        TypeDosage

                        Guidance on how to interpret the contents of this table can be foundhere

                        0. MedicationDispense
                        Definition

                        Indicates that a medication product is to be or has been dispensed for a named person/patient. This includes a description of the medication product (supply) provided and the instructions for administering the medication. The medication dispense is the result of a pharmacy system responding to a medication order.

                        ShortMedicationDispense
                        Comments

                        The WG will be updating the MedicationDispense resource to adjust each affected resource to align with the workflow pattern (see workflow.html).

                        Control0..*
                        Alternate NamesVerstrekking
                        Invariantsdom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources (contained.contained.empty())
                        dom-1: If the resource is contained in another resource, it SHALL NOT contain any narrative (contained.text.empty())
                        dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated (contained.meta.versionId.empty() and contained.meta.lastUpdated.empty())
                        dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource (contained.where(('#'+id in %resource.descendants().reference).not()).empty())
                        mdd-1: whenHandedOver cannot be before whenPrepared (whenHandedOver.empty() or whenPrepared.empty() or whenHandedOver >= whenPrepared)
                        2. MedicationDispense.id
                        Definition

                        The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.

                        ShortLogical id of this artifact
                        Comments

                        The only time that a resource does not have an id is when it is being submitted to the server using a create operation.

                        Control0..1
                        Typeid
                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                        Summarytrue
                        4. MedicationDispense.meta
                        Definition

                        The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content may not always be associated with version changes to the resource.

                        ShortMetadata about the resource
                        Control0..1
                        TypeMeta
                        Summarytrue
                        6. MedicationDispense.implicitRules
                        Definition

                        A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content.

                        ShortA set of rules under which this content was created
                        Comments

                        Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element.

                        This element is labelled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation.

                        Control0..1
                        Typeuri
                        Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                        Summarytrue
                        8. MedicationDispense.language
                        Definition

                        The base language in which the resource is written.

                        ShortLanguage of the resource content
                        Comments

                        Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).

                        Control0..1
                        BindingUnless not suitable, these codes SHALL be taken from Common Languages
                        (extensible to http://hl7.org/fhir/ValueSet/languages|3.0.2)

                        A human language.

                        Additional BindingsPurpose
                        All LanguagesMax Binding
                        Typecode
                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                        10. MedicationDispense.text
                        Definition

                        A human-readable narrative that contains a summary of the resource, and may be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.

                        ShortText summary of the resource, for human interpretation
                        Comments

                        Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded in formation is added later.

                        Control0..1
                        This element is affected by the following invariants: dom-1
                        TypeNarrative
                        Alternate Namesnarrative, html, xhtml, display
                        12. MedicationDispense.contained
                        Definition

                        These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.

                        ShortContained, inline Resources
                        Comments

                        This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again.

                        Control0..*
                        TypeResource
                        Alternate Namesinline resources, anonymous resources, contained resources
                        14. MedicationDispense.extension
                        Definition

                        An Extension

                        ShortExtension
                        Control0..*
                        TypeExtension
                        SlicingThis element introduces a set of slices on MedicationDispense.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                        • value @ url
                        • 16. MedicationDispense.extension:distributionForm
                          Slice NamedistributionForm
                          Definition

                          Distribution form.

                          ShortDistributionForm
                          Comments

                          For example through Baxter or seperate box.

                          Control0..1
                          This element is affected by the following invariants: ele-1
                          TypeExtension(HCIM Dispense Distribution Form) (Extension Type: CodeableConcept)
                          Alternate NamesDistributievorm
                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                          ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                          18. MedicationDispense.extension:distributionForm.id
                          Definition

                          unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                          Shortxml:id (or equivalent in JSON)
                          Control0..1
                          Typestring
                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                          XML FormatIn the XML format, this property is represented as an attribute.
                          20. MedicationDispense.extension:distributionForm.extension
                          Definition

                          May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                          ShortAdditional Content defined by implementations
                          Comments

                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                          Control0..*
                          TypeExtension
                          Alternate Namesextensions, user content
                          SlicingThis element introduces a set of slices on MedicationDispense.extension.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                          • value @ url
                          • 22. MedicationDispense.extension:distributionForm.url
                            Definition

                            Source of the definition for the extension code - a logical name or a URL.

                            Shortidentifies the meaning of the extension
                            Comments

                            The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

                            Control1..1
                            Typeuri
                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                            XML FormatIn the XML format, this property is represented as an attribute.
                            Fixed Valuehttp://nictiz.nl/fhir/StructureDefinition/zib-Dispense-DistributionForm
                            24. MedicationDispense.extension:distributionForm.value[x]
                            Definition

                            Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

                            ShortValue of extension
                            Control0..1
                            TypeCodeableConcept
                            [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                            SlicingThis element introduces a set of slices on MedicationDispense.extension.value[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
                            • type @ $this
                            • 26. MedicationDispense.extension:distributionForm.value[x]:valueCodeableConcept
                              Slice NamevalueCodeableConcept
                              Definition

                              Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

                              ShortValue of extension
                              Control0..1
                              BindingUnless not suitable, these codes SHALL be taken from MedicatieverstrekkingDistributievormCodelijst
                              (extensible to http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.9.1--20171231000000)

                              VerstrekkingDistributievormCodelijst

                              TypeCodeableConcept
                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                              28. MedicationDispense.extension:requestDate
                              Slice NamerequestDate
                              Definition

                              The time at which a pharmacist records an intended dispense.

                              ShortRequestDate
                              Control0..1
                              This element is affected by the following invariants: ele-1
                              TypeExtension(HCIM Dispense RequestDate) (Extension Type: dateTime)
                              Alternate NamesAanschrijfdatum
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                              30. MedicationDispense.extension:additionalInformation
                              Slice NameadditionalInformation
                              Definition

                              Additional information includes details on the structure of the dispense. This can be e.g. a reason for deviating from the dispense request. For now, this list is used. This list will be replaced by a thesaurus in the G standard at a later stage.

                              ShortDispenseAdditionalInformation
                              Control0..1
                              This element is affected by the following invariants: ele-1
                              TypeExtension(HCIM AdditionalInformation) (Extension Type: CodeableConcept)
                              Alternate NamesVerstrekkingAanvullendeInformatie
                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                              ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                              32. MedicationDispense.extension:additionalInformation.id
                              Definition

                              unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                              Shortxml:id (or equivalent in JSON)
                              Control0..1
                              Typestring
                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                              XML FormatIn the XML format, this property is represented as an attribute.
                              34. MedicationDispense.extension:additionalInformation.extension
                              Definition

                              May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                              ShortAdditional Content defined by implementations
                              Comments

                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                              Control0..*
                              TypeExtension
                              Alternate Namesextensions, user content
                              SlicingThis element introduces a set of slices on MedicationDispense.extension.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                              • value @ url
                              • 36. MedicationDispense.extension:additionalInformation.url
                                Definition

                                Source of the definition for the extension code - a logical name or a URL.

                                Shortidentifies the meaning of the extension
                                Comments

                                The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.

                                Control1..1
                                Typeuri
                                Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                XML FormatIn the XML format, this property is represented as an attribute.
                                Fixed Valuehttp://nictiz.nl/fhir/StructureDefinition/zib-Medication-AdditionalInformation
                                38. MedicationDispense.extension:additionalInformation.value[x]
                                Definition

                                Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

                                ShortValue of extension
                                Control0..1
                                TypeCodeableConcept
                                [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                SlicingThis element introduces a set of slices on MedicationDispense.extension.value[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
                                • type @ $this
                                • 40. MedicationDispense.extension:additionalInformation.value[x]:valueCodeableConcept
                                  Slice NamevalueCodeableConcept
                                  Definition

                                  Value of extension - may be a resource or one of a constrained set of the data types (see Extensibility in the spec for list).

                                  ShortValue of extension
                                  Control0..1
                                  BindingUnless not suitable, these codes SHALL be taken from MedicatieverstrekkingAanvullendeInformatieCodelijst
                                  (extensible to http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.9.9.2--20171231000000)

                                  VerstrekkingAanvullendeInformatieCodelijst

                                  TypeCodeableConcept
                                  [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                  ExampleExample of DispenseAdditionalInformation: { "coding" : [{ "system" : "urn:oid:2.16.840.1.113883.2.4.3.11.60.20.77.5.2.3.2052", "code" : "1", "display" : "Aantal bewust gewijzigd" }] }
                                  42. MedicationDispense.extension:medicationTreatment
                                  Slice NamemedicationTreatment
                                  Definition

                                  This extension is to describe which overarching medication treatment this information is part of. This is done by the use of an identifier of that medication treatment.

                                  ShortMedication Treatment
                                  Comments

                                  No HCIM concept is available for this element. Therefore a mapping to the relevant element Medication Process data element is provided.

                                  Control0..1
                                  This element is affected by the following invariants: ele-1
                                  TypeExtension(HCIM MedicationTreatment) (Extension Type: Identifier)
                                  Alternate NamesMedicamenteuze behandeling
                                  Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                                  ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
                                  44. MedicationDispense.modifierExtension
                                  Definition

                                  May be used to represent additional information that is not part of the basic definition of the resource, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                  ShortExtensions that cannot be ignored
                                  Comments

                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                  Control0..*
                                  TypeExtension
                                  Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                                  Alternate Namesextensions, user content
                                  46. MedicationDispense.identifier
                                  Definition

                                  Identifier assigned by the dispensing facility - this is an identifier assigned outside FHIR.

                                  ShortExternal identifier
                                  NoteThis is a business identifier, not a resource identifier (see discussion)
                                  Control0..*
                                  TypeIdentifier
                                  48. MedicationDispense.partOf
                                  Definition

                                  The procedure that the dispense is done because of.

                                  ShortEvent that dispense is part of
                                  Control0..*
                                  TypeReference(HCIM Procedure)
                                  50. MedicationDispense.status
                                  Definition

                                  A code specifying the state of the set of dispense events.

                                  Shortpreparation | in-progress | on-hold | completed | entered-in-error | stopped
                                  Comments

                                  This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.

                                  Control0..1
                                  BindingThe codes SHALL be taken from MedicationDispenseStatus
                                  (required to http://hl7.org/fhir/ValueSet/medication-dispense-status|3.0.2)

                                  A coded concept specifying the state of the dispense event.

                                  Typecode
                                  Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                  Summarytrue
                                  52. MedicationDispense.category
                                  Definition

                                  Indicates type of medication dispense and where the medication is expected to be consumed or administered.

                                  ShortType of medication dispense
                                  Control1..1
                                  BindingThe codes SHOULD be taken from MedicationDispenseCategory
                                  (preferred to http://hl7.org/fhir/ValueSet/medication-dispense-category|3.0.2)

                                  A code describing where the dispensed medication is expected to be consumed or administered

                                  TypeCodeableConcept
                                  54. MedicationDispense.category.id
                                  Definition

                                  unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                  Shortxml:id (or equivalent in JSON)
                                  Control0..1
                                  Typestring
                                  Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                  XML FormatIn the XML format, this property is represented as an attribute.
                                  56. MedicationDispense.category.extension
                                  Definition

                                  May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                  ShortAdditional Content defined by implementations
                                  Comments

                                  There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                  Control0..*
                                  TypeExtension
                                  Alternate Namesextensions, user content
                                  SlicingThis element introduces a set of slices on MedicationDispense.category.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                  • value @ url
                                  • 58. MedicationDispense.category.coding
                                    Definition

                                    A reference to a code defined by a terminology system.

                                    ShortCode defined by a terminology system
                                    Comments

                                    Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

                                    Control0..*
                                    TypeCoding
                                    Summarytrue
                                    Requirements

                                    Allows for translations and alternate encodings within a code system. Also supports communication of the same instance to systems requiring different encodings.

                                    SlicingThis element introduces a set of slices on MedicationDispense.category.coding. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                    • value @ code
                                    • 60. MedicationDispense.category.coding:DispenseCode
                                      Slice NameDispenseCode
                                      Definition

                                      Category SNOMED code used for indexing/retrieval of the HCIM Dispense. The SNOMED code 373784005 for this resource is stated in the Medication Process v09.

                                      ShortDispenseCode
                                      Comments

                                      Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

                                      Control0..*
                                      TypeCoding
                                      Summarytrue
                                      Requirements

                                      Allows for translations and alternate encodings within a code system. Also supports communication of the same instance to systems requiring different encodings.

                                      62. MedicationDispense.category.coding:DispenseCode.id
                                      Definition

                                      unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                      Shortxml:id (or equivalent in JSON)
                                      Control0..1
                                      Typestring
                                      Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                      XML FormatIn the XML format, this property is represented as an attribute.
                                      64. MedicationDispense.category.coding:DispenseCode.extension
                                      Definition

                                      May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                      ShortAdditional Content defined by implementations
                                      Comments

                                      There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                      Control0..*
                                      TypeExtension
                                      Alternate Namesextensions, user content
                                      SlicingThis element introduces a set of slices on MedicationDispense.category.coding.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                      • value @ url
                                      • 66. MedicationDispense.category.coding:DispenseCode.system
                                        Definition

                                        The identification of the code system that defines the meaning of the symbol in the code.

                                        ShortIdentity of the terminology system
                                        Comments

                                        The URI may be an OID (urn:oid:...) or a UUID (urn:uuid:...). OIDs and UUIDs SHALL be references to the HL7 OID registry. Otherwise, the URI should come from HL7's list of FHIR defined special URIs or it should de-reference to some definition that establish the system clearly and unambiguously.

                                        Control0..1
                                        Typeuri
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Summarytrue
                                        Requirements

                                        Need to be unambiguous about the source of the definition of the symbol.

                                        Fixed Valuehttp://snomed.info/sct
                                        68. MedicationDispense.category.coding:DispenseCode.version
                                        Definition

                                        The version of the code system which was used when choosing this code. Note that a well-maintained code system does not need the version reported, because the meaning of codes is consistent across versions. However this cannot consistently be assured. and when the meaning is not guaranteed to be consistent, the version SHOULD be exchanged.

                                        ShortVersion of the system - if relevant
                                        Comments

                                        Where the terminology does not clearly define what string should be used to identify code system versions, the recommendation is to use the date (expressed in FHIR date format) on which that version was officially published as the version date.

                                        NoteThis is a business version Id, not a resource version Id (see discussion)
                                        Control0..1
                                        Typestring
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Summarytrue
                                        70. MedicationDispense.category.coding:DispenseCode.code
                                        Definition

                                        A symbol in syntax defined by the system. The symbol may be a predefined code or an expression in a syntax defined by the coding system (e.g. post-coordination).

                                        ShortSymbol in syntax defined by the system
                                        Control0..1
                                        Typecode
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Summarytrue
                                        Requirements

                                        Need to refer to a particular code in the system.

                                        Fixed Value373784005
                                        72. MedicationDispense.category.coding:DispenseCode.display
                                        Definition

                                        A representation of the meaning of the code in the system, following the rules of the system.

                                        ShortRepresentation defined by the system
                                        Control0..1
                                        Typestring
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Summarytrue
                                        Requirements

                                        Need to be able to carry a human-readable meaning of the code for readers that do not know the system.

                                        74. MedicationDispense.category.coding:DispenseCode.userSelected
                                        Definition

                                        Indicates that this coding was chosen by a user directly - i.e. off a pick list of available items (codes or displays).

                                        ShortIf this coding was chosen directly by the user
                                        Comments

                                        Amongst a set of alternatives, a directly chosen code is the most appropriate starting point for new translations. There is some ambiguity about what exactly 'directly chosen' implies, and trading partner agreement may be needed to clarify the use of this element and its consequences more completely.

                                        Control0..1
                                        Typeboolean
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Summarytrue
                                        Requirements

                                        This has been identified as a clinical safety criterium - that this exact system/code pair was chosen explicitly, rather than inferred by the system based on some rules or language processing.

                                        76. MedicationDispense.category.text
                                        Definition

                                        A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.

                                        ShortPlain text representation of the concept
                                        Comments

                                        Very often the text is the same as a displayName of one of the codings.

                                        Control0..1
                                        Typestring
                                        Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                        Summarytrue
                                        Requirements

                                        The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.

                                        78. MedicationDispense.medication[x]
                                        Definition

                                        Identifies the medication being administered. This is either a link to a resource representing the details of the medication or a simple attribute carrying a code that identifies the medication from a known list of medications.

                                        ShortWhat medication was supplied
                                        Comments

                                        If only a code is specified, then it needs to be a code for a specific product. If more information is required, then the use of the medication resource is recommended.  For example if you require form or lot number, then you must reference the Medication resource. .

                                        Control1..1
                                        TypeReference
                                        [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                        Summarytrue
                                        SlicingThis element introduces a set of slices on MedicationDispense.medication[x]. The slices areUnordered and Closed, and can be differentiated using the following discriminators:
                                        • type @ $this
                                        • 80. MedicationDispense.medication[x]:medicationReference
                                          Slice NamemedicationReference
                                          Definition

                                          The dispensed medicine.

                                          ShortDispensedMedicine
                                          Control1..1
                                          TypeReference(HCIM PharmaceuticalProduct)
                                          [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                          Summarytrue
                                          Alternate NamesVerstrekGeneesmiddel
                                          82. MedicationDispense.subject
                                          Definition

                                          A link to a resource representing the person or the group to whom the medication will be given.

                                          ShortWho the dispense is for
                                          Comments

                                          SubstanceAdministration->subject->Patient.

                                          Control0..1
                                          TypeReference(nl-core-patient, Group)
                                          Summarytrue
                                          84. MedicationDispense.context
                                          Definition

                                          The encounter or episode of care that establishes the context for this event.

                                          ShortEncounter / Episode associated with event
                                          Control0..1
                                          TypeReference(HCIM Encounter, nl-core-episodeofcare)
                                          86. MedicationDispense.supportingInformation
                                          Definition

                                          Additional information that supports the medication being dispensed.

                                          ShortInformation that supports the dispensing of the medication
                                          Control0..*
                                          TypeReference(Resource)
                                          88. MedicationDispense.performer
                                          Definition

                                          In almost all cases, the supplier will be a pharmacist. It could also be supplied by a webshop (in case of an online order), a drug store or a foreign pharmacist.

                                          ShortSupplier
                                          Comments

                                          The performer will be reviewed as part of STU4.

                                          Control0..*
                                          TypeBackboneElement
                                          Alternate NamesVerstrekker
                                          Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                                          90. MedicationDispense.performer.id
                                          Definition

                                          unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                          Shortxml:id (or equivalent in JSON)
                                          Control0..1
                                          Typestring
                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                          XML FormatIn the XML format, this property is represented as an attribute.
                                          92. MedicationDispense.performer.extension
                                          Definition

                                          May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                          ShortAdditional Content defined by implementations
                                          Comments

                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                          Control0..*
                                          TypeExtension
                                          Alternate Namesextensions, user content
                                          94. MedicationDispense.performer.modifierExtension
                                          Definition

                                          May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                          ShortExtensions that cannot be ignored
                                          Comments

                                          There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                          Control0..*
                                          TypeExtension
                                          Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                                          Summarytrue
                                          Alternate Namesextensions, user content, modifiers
                                          96. MedicationDispense.performer.actor
                                          Definition

                                          The device, practitioner, etc. who performed the action. It should be assumed that the actor is the dispenser of the medication.

                                          ShortIndividual who was performing
                                          Comments

                                          The health professional's speciality, role, and organization are captured and communicated through the PractitionerRole Resource based on the nl-core-practitionerrole profile.

                                          Control1..1
                                          TypeReference(nl-core-practitioner, nl-core-organization, nl-core-patient, HCIM MedicalDevice Product, nl-core-relatedperson)
                                          98. MedicationDispense.performer.actor.id
                                          Definition

                                          unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                          Shortxml:id (or equivalent in JSON)
                                          Control0..1
                                          Typestring
                                          Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                          XML FormatIn the XML format, this property is represented as an attribute.
                                          100. MedicationDispense.performer.actor.extension
                                          Definition

                                          An Extension

                                          ShortExtension
                                          Control0..*
                                          TypeExtension
                                          SlicingThis element introduces a set of slices on MedicationDispense.performer.actor.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                          • value @ url
                                          • 102. MedicationDispense.performer.actor.extension:practitionerRole
                                            Slice NamepractitionerRole
                                            Definition

                                            Optional Extension Element - found in all resources.

                                            ShortOptional Extensions Element
                                            Control0..1
                                            TypeExtension(PractitionerRole Reference) (Extension Type: Reference)
                                            104. MedicationDispense.performer.actor.reference
                                            Definition

                                            A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.

                                            ShortLiteral reference, Relative, internal or absolute URL
                                            Comments

                                            Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries. Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure "/[type]/[id]" then it should be assumed that the reference is to a FHIR RESTful server.

                                            Control0..1
                                            This element is affected by the following invariants: ref-1
                                            Typestring
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            106. MedicationDispense.performer.actor.identifier
                                            Definition

                                            An identifier for the other resource. This is used when there is no way to reference the other resource directly, either because the entity is not available through a FHIR server, or because there is no way for the author of the resource to convert a known identifier to an actual location. There is no requirement that a Reference.identifier point to something that is actually exposed as a FHIR instance, but it SHALL point to a business concept that would be expected to be exposed as a FHIR instance, and that instance would need to be of a FHIR resource type allowed by the reference.

                                            ShortLogical reference, when literal reference is not known
                                            Comments

                                            When an identifier is provided in place of a reference, any system processing the reference will only be able to resolve the identifier to a reference if it understands the business context in which the identifier is used. Sometimes this is global (e.g. a national identifier) but often it is not. For this reason, none of the useful mechanisms described for working with references (e.g. chaining, includes) are possible, nor should servers be expected to be able resolve the reference. Servers may accept an identifier based reference untouched, resolve it, and/or reject it - see CapabilityStatement.rest.resource.referencePolicy.

                                            When both an identifier and a literal reference are provided, the literal reference is preferred. Applications processing the resource are allowed - but not required - to check that the identifier matches the literal reference

                                            Applications converting a logical reference to a literal reference may choose to leave the logical reference present, or remove it.

                                            NoteThis is a business identifier, not a resource identifier (see discussion)
                                            Control0..1
                                            TypeIdentifier
                                            Summarytrue
                                            108. MedicationDispense.performer.actor.display
                                            Definition

                                            Plain text narrative that identifies the resource in addition to the resource reference.

                                            ShortText alternative for the resource
                                            Comments

                                            This is generally not the same as the Resource.text of the referenced resource. The purpose is to identify what's being referenced, not to fully describe it.

                                            Control0..1
                                            Typestring
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            110. MedicationDispense.performer.onBehalfOf
                                            Definition

                                            The organization the device or practitioner was acting on behalf of.

                                            ShortOrganization organization was acting for
                                            Control0..1
                                            TypeReference(nl-core-organization)
                                            112. MedicationDispense.authorizingPrescription
                                            Definition

                                            Relationship to the dispense request.

                                            ShortDispenseRequest
                                            Comments

                                            Maps to basedOn in Event logical model.

                                            Control0..1
                                            TypeReference(HCIM DispenseRequest)
                                            Alternate NamesVerstrekkingsverzoek
                                            114. MedicationDispense.type
                                            Definition

                                            Indicates the type of dispensing event that is performed. For example, Trial Fill, Completion of Trial, Partial Fill, Emergency Fill, Samples, etc.

                                            ShortTrial fill, partial fill, emergency fill, etc.
                                            Control0..1
                                            BindingFor example codes, see ActPharmacySupplyType|2014-03-26
                                            (example to http://hl7.org/fhir/ValueSet/v3-ActPharmacySupplyType|2014-03-26)

                                            Indicates the type of dispensing event that is performed. For example, Trial Fill, Completion of Trial, Partial Fill, Emergency Fill, Samples, etc.

                                            TypeCodeableConcept
                                            116. MedicationDispense.quantity
                                            Definition

                                            Number of units of the product (measured based on the relevant product code) supplied.

                                            ShortDispensedAmount
                                            Control0..1
                                            TypeQuantity(SimpleQuantity)
                                            Alternate NamesVerstrekteHoeveelheid
                                            118. MedicationDispense.daysSupply
                                            Definition

                                            The period in which the medication is expected to be used. The value depends on the dose and the dispensed amount.

                                            ShortDurationOfUse
                                            Control0..1
                                            TypeQuantity(SimpleQuantity)
                                            Alternate NamesVerbruiksDuur
                                            120. MedicationDispense.whenPrepared
                                            Definition

                                            The time when the dispensed product was packaged and reviewed.

                                            ShortWhen product was packaged and reviewed
                                            Control0..1
                                            TypedateTime
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Summarytrue
                                            122. MedicationDispense.whenHandedOver
                                            Definition

                                            The time at which the medicine was supplied. The date and time at which the medicine is delivered.
                                            Note: this is the time at which the medicine was delivered to the patient (or their administrator/representative) and not the request date.

                                            ShortDispenseDateTime
                                            Control0..1
                                            TypedateTime
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            Alternate NamesVerstrekkingsDatumTijd
                                            ExampleExample of DispenseDateTime: 2017-05-17
                                            124. MedicationDispense.destination
                                            Definition

                                            Dispense location.

                                            ShortDispenseLocation
                                            Control0..1
                                            TypeReference(nl-core-location)
                                            Alternate NamesAfleverlocatie
                                            126. MedicationDispense.receiver
                                            Definition

                                            Identifies the person who picked up the medication. This will usually be a patient or their caregiver, but some cases exist where it can be a healthcare professional.

                                            ShortWho collected the medication
                                            Control0..*
                                            TypeReference(nl-core-patient, nl-core-practitioner)
                                            128. MedicationDispense.receiver.id
                                            Definition

                                            unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                            Shortxml:id (or equivalent in JSON)
                                            Control0..1
                                            Typestring
                                            Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                            XML FormatIn the XML format, this property is represented as an attribute.
                                            130. MedicationDispense.receiver.extension
                                            Definition

                                            An Extension

                                            ShortExtension
                                            Control0..*
                                            TypeExtension
                                            SlicingThis element introduces a set of slices on MedicationDispense.receiver.extension. The slices areUnordered and Open, and can be differentiated using the following discriminators:
                                            • value @ url
                                            • 132. MedicationDispense.receiver.extension:practitionerRole
                                              Slice NamepractitionerRole
                                              Definition

                                              Optional Extension Element - found in all resources.

                                              ShortOptional Extensions Element
                                              Control0..1
                                              TypeExtension(PractitionerRole Reference) (Extension Type: Reference)
                                              134. MedicationDispense.receiver.reference
                                              Definition

                                              A reference to a location at which the other resource is found. The reference may be a relative reference, in which case it is relative to the service base URL, or an absolute URL that resolves to the location where the resource is found. The reference may be version specific or not. If the reference is not to a FHIR RESTful server, then it should be assumed to be version specific. Internal fragment references (start with '#') refer to contained resources.

                                              ShortLiteral reference, Relative, internal or absolute URL
                                              Comments

                                              Using absolute URLs provides a stable scalable approach suitable for a cloud/web context, while using relative/logical references provides a flexible approach suitable for use when trading across closed eco-system boundaries. Absolute URLs do not need to point to a FHIR RESTful server, though this is the preferred approach. If the URL conforms to the structure "/[type]/[id]" then it should be assumed that the reference is to a FHIR RESTful server.

                                              Control0..1
                                              This element is affected by the following invariants: ref-1
                                              Typestring
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Summarytrue
                                              136. MedicationDispense.receiver.identifier
                                              Definition

                                              An identifier for the other resource. This is used when there is no way to reference the other resource directly, either because the entity is not available through a FHIR server, or because there is no way for the author of the resource to convert a known identifier to an actual location. There is no requirement that a Reference.identifier point to something that is actually exposed as a FHIR instance, but it SHALL point to a business concept that would be expected to be exposed as a FHIR instance, and that instance would need to be of a FHIR resource type allowed by the reference.

                                              ShortLogical reference, when literal reference is not known
                                              Comments

                                              When an identifier is provided in place of a reference, any system processing the reference will only be able to resolve the identifier to a reference if it understands the business context in which the identifier is used. Sometimes this is global (e.g. a national identifier) but often it is not. For this reason, none of the useful mechanisms described for working with references (e.g. chaining, includes) are possible, nor should servers be expected to be able resolve the reference. Servers may accept an identifier based reference untouched, resolve it, and/or reject it - see CapabilityStatement.rest.resource.referencePolicy.

                                              When both an identifier and a literal reference are provided, the literal reference is preferred. Applications processing the resource are allowed - but not required - to check that the identifier matches the literal reference

                                              Applications converting a logical reference to a literal reference may choose to leave the logical reference present, or remove it.

                                              NoteThis is a business identifier, not a resource identifier (see discussion)
                                              Control0..1
                                              TypeIdentifier
                                              Summarytrue
                                              138. MedicationDispense.receiver.display
                                              Definition

                                              Plain text narrative that identifies the resource in addition to the resource reference.

                                              ShortText alternative for the resource
                                              Comments

                                              This is generally not the same as the Resource.text of the referenced resource. The purpose is to identify what's being referenced, not to fully describe it.

                                              Control0..1
                                              Typestring
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              Summarytrue
                                              140. MedicationDispense.note
                                              Definition

                                              Comments or additional information on the dispense. Additional information includes details on the structure of the dispense. This can be e.g. a reason for deviating from the dispense request.

                                              ShortComment
                                              Control0..*
                                              TypeAnnotation
                                              Alternate NamesToelichting, Aanvullende informatie
                                              142. MedicationDispense.dosageInstruction
                                              Definition

                                              Dosage instructions are part of an AdministrationAgreement

                                              ShortHow the medication is to be used by the patient or administered by the caregiver
                                              Comments

                                              When the dose or rate is intended to change over the entire administration period (e.g. Tapering dose prescriptions), multiple instances of dosage instructions will need to be supplied to convey the different doses/rates. The pharmacist reviews the medication order prior to dispense and updates the dosageInstruction based on the actual product being dispensed.

                                              Control0..0
                                              TypeDosage
                                              144. MedicationDispense.substitution
                                              Definition

                                              Indicates whether or not substitution was made as part of the dispense. In some cases substitution will be expected but does not happen, in other cases substitution is not expected but does happen. This block explains what substitution did or did not happen and why. If nothing is specified, substitution was not done.

                                              ShortWhether a substitution was performed on the dispense
                                              Control0..1
                                              TypeBackboneElement
                                              Invariantsele-1: All FHIR elements must have a @value or children (hasValue() | (children().count() > id.count()))
                                              146. MedicationDispense.substitution.id
                                              Definition

                                              unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

                                              Shortxml:id (or equivalent in JSON)
                                              Control0..1
                                              Typestring
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              XML FormatIn the XML format, this property is represented as an attribute.
                                              148. MedicationDispense.substitution.extension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

                                              ShortAdditional Content defined by implementations
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Alternate Namesextensions, user content
                                              150. MedicationDispense.substitution.modifierExtension
                                              Definition

                                              May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

                                              ShortExtensions that cannot be ignored
                                              Comments

                                              There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

                                              Control0..*
                                              TypeExtension
                                              Is Modifiertrue because No Modifier Reason provideed in previous versions of FHIR
                                              Summarytrue
                                              Alternate Namesextensions, user content, modifiers
                                              152. MedicationDispense.substitution.wasSubstituted
                                              Definition

                                              True if the dispenser dispensed a different drug or product from what was prescribed.

                                              ShortWhether a substitution was or was not performed on the dispense
                                              Control1..1
                                              Typeboolean
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              154. MedicationDispense.substitution.type
                                              Definition

                                              A code signifying whether a different drug was dispensed from what was prescribed.

                                              ShortCode signifying whether a different drug was dispensed from what was prescribed
                                              Control0..1
                                              BindingFor example codes, see ActSubstanceAdminSubstitutionCode|2014-03-26
                                              (example to http://hl7.org/fhir/ValueSet/v3-ActSubstanceAdminSubstitutionCode|2014-03-26)

                                              A coded concept describing whether a different medicinal product may be dispensed other than the product as specified exactly in the prescription

                                              TypeCodeableConcept
                                              156. MedicationDispense.substitution.reason
                                              Definition

                                              Indicates the reason for the substitution of (or lack of substitution) from what was prescribed.

                                              ShortWhy was substitution made
                                              Control0..*
                                              BindingFor example codes, see SubstanceAdminSubstitutionReason|2014-03-26
                                              (example to http://hl7.org/fhir/ValueSet/v3-SubstanceAdminSubstitutionReason|2014-03-26)

                                              A coded concept describing the reason that a different medication should (or should not) be substituted from what was prescribed

                                              TypeCodeableConcept
                                              158. MedicationDispense.substitution.responsibleParty
                                              Definition

                                              The person or organization that has primary responsibility for the substitution.

                                              ShortWho is responsible for the substitution
                                              Control0..*
                                              TypeReference(Practitioner)
                                              160. MedicationDispense.detectedIssue
                                              Definition

                                              Indicates an actual or potential clinical issue with or between one or more active or proposed clinical actions for a patient; e.g. Drug-drug interaction, duplicate therapy, dosage alert etc.

                                              ShortClinical issue with action
                                              Control0..*
                                              TypeReference(DetectedIssue)
                                              Alternate NamesContraindication, Drug Utilization Review (DUR), Alert
                                              162. MedicationDispense.notDone
                                              Definition

                                              True if the dispense was not performed for some reason.

                                              ShortWhether the dispense was or was not performed
                                              Control0..1
                                              Typeboolean
                                              Primitive ValueThis primitive element may be present, or absent, or replaced by an extension
                                              164. MedicationDispense.notDoneReason[x]
                                              Definition

                                              Indicates the reason why a dispense was not performed.

                                              ShortWhy a dispense was not performed
                                              Control0..1
                                              TypeChoice of: CodeableConcept, Reference(DetectedIssue)
                                              [x] NoteSeeChoice of Data Typesfor further information about how to use [x]
                                              166. MedicationDispense.eventHistory
                                              Definition

                                              A summary of the events of interest that have occurred, such as when the dispense was verified.

                                              ShortA list of releveant lifecycle events
                                              Comments

                                              This may not include provenances for all versions of the request – only those deemed “relevant” or important. This SHALL NOT include the Provenance associated with this current version of the resource. (If that provenance is deemed to be a “relevant” change, it will need to be added as part of a later update. Until then, it can be queried directly as the Provenance that points to this version using _revinclude All Provenances should have some historical version of this Request as their subject.).

                                              Control0..*
                                              TypeReference(Provenance)